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Aims to build a database designed to store full descriptions of interactions, molecular complexes and pathways.
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Aims to build a database designed to store full descriptions of interactions, molecular complexes and pathways.
EXPLORE >   Projects >  Biomolecular Interaction Network Database (BIND)
Biomolecular Interaction Network Database (BIND)
OBJECTIVES
TEAM
APPROACH
IMPACT
INTELLECTUAL PROPERTY
Objectives
The aim of this project was to scale-up and populate the Biomolecular Interaction Network Database (BIND), which collects high-quality biomolecular data. The majority of interactions reported in this database include protein-protein, protein-DNA, and protein-small molecule interactions.
Project Information
Started: 2002
Ended: 2005

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Team
BIND was led by Dr. Christopher Hogue at the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto. It had more than 56 collaborators at 49 research centres around the world.


Approach
The information used to populate this database was obtained from published data and carefully examined by human curators. This massive effort resulted in a comprehensive, non-redundant collection of biomolecular interactions.
Project Information
Started: 2002
Ended: 2005

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Impact
BIND represented one of the largest curated databases of biomolecular interactions. At the end of the project, it contained more than 200 000 interactions obtained from 77 journals and 23 376 publications. In addition, the project led to the development of several interaction prediction algorithms: the SMID-Genomes, which predicts small molecule interactions with genomic information, and Armadillo, which predicts the location of protein linkages. Furthermore, BIND’s interface and new software protocols have been implemented by other major databases including SGD and Flybase. It is anticipated that numerous research programs have benefited from the database because the biomolecular interactions contained within the BIND database are the basis of all cellular activities.

After the project ended in August 2005, the IP for BIND was secured by Unleashed Informatics. In March 2007, Unleashed Informatics was acquired by Thomson Corporation.
Project Information
Started: 2002
Ended: 2005

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Intellectual Property

Project Information
Started: 2002
Ended: 2005

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CATEGORIES
Application Area
Human health
Core Technology
data curation, prediction algorithms
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