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I am a graduate student with interests in cheminformatics and biological applications of classical artificial intelligence.
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I am a graduate student with interests in cheminformatics and biological applications of classical artificial intelligence.
EXPLORE >   Researchers >  Abraham Heifets
Abraham Heifets |
University of Toronto (UofT)
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Research
I am interested in cheminformatics topics such as synthetic feasibility prediction,automated retrosynthetic analysis,and chemical space as elucidated in the patent literature.
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Biography

Abraham Heifets is a PhD candidate in the Department of Computer Science at the University of Toronto and a member of the Ontario Cancer Institute, University Health Network of research hospitals, MaRS, Terrence Donnelly Centre for Cellular and Biomolecular Research, and the IBM Life Sciences Discovery Centre. He is supervised by Prof. Igor Jurisica. He received his Bachelors and Masters degrees from Cornell University.

Currently, Abraham applies classical artificial intelligence techniques to organic synthesis planning. Prior to attending the University of Toronto, he explored high-performance processing of XML at the IBM T.J. Watson Research Center. Previously, he worked on a world champion robotic soccer team, a publish-subscribe system for location-based services, and single-agent search algorithms.

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Key Publications
Heifets, A., Jurisica, I., SCRIPDB: a portal for easy access to syntheses, chemicals and reactions in patents. Nucleic Acids Research. 2011
Heifets, A., Lilien, R., LigAlign: Flexible ligand-based active site alignment and analysis. Journal of Molecular Graphics and Modelling. Volume 29, Issue 1, 24 August 2010, Pages 93-101.
Matsa, M., Perkins, E., Heifets, A., Kostoulas M. G., Silva, D., Mendelsohn, N., Leger, M. A High-Performance Interpretive Approach to Schema-Directed Parsing. Proceedings of the 16th International Conference on World Wide Web (Banff, Canada, May 8 - 12, 2007). WWW '07. ACM Press, New York, NY, 1093-1102.
Kostoulas, M. G., Matsa, M., Mendelsohn, N., Perkins, E., Heifets, A., and Mercaldi, M. XML Screamer: an integrated approach to high performance XML parsing, validation and deserialization. Proceedings of the 15th International Conference on World Wide Web (Edinburgh, Scotland, May 23 - 26, 2006). WWW '06. ACM Press, New York, NY, 93-102.
Perkins, E., Matsa, M., Kostoulas, M. G., Heifets, A., and Mendelsohn, N. 2006. Generation of efficient parsers through direct compilation of XML Schema grammars. IBM Systems Journal 45(2):225-245. 2006.
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Intellectual Property

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CATEGORIES
Application Area
Human health
Disciplinary Focus
Informatics, theoretical biology and computer science
Research Paradigm
Large-scale projects, Technology development
Core Technology
Other molecules: High-throughput small molecule screening
Organism
Human
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