-Phenotype discovery and phenogenomics (Pathology phenotyping of mouse models of human disease for gene effect and drug effect)
-Cryobiology and in vitro fertilization (Cryopreservation & IVF)
-Rodent models of genetic and infectious lung disease (Asthma phenogenomics)
-Phenotype informatics and morphology data visualization (Phenogenomic data integration & visualization)

Dr. McKerlie is a veterinary pathologist and phenogenomic scientist. He came to SickKids in June 2002 from the Research Institute at Sunnybrook & Women's College where he was Director of the Department of Comparative Research. He received his DVM from the Ontario Veterinary College at the University of Guelph in 1991, his MRCVS from the Royal College of Veterinary Surgeons in London, and his DVSc in comparative pathology from the University of Guelph in 1997.

In addition to his appointment at SickKids, Dr. McKerlie is Interim CEO of the Toronto Centre for Phenogenomics, a new research-enabling centre that is among the largest genetics centres in the world dedicated to the development and study of mouse models of human disease. Dr. McKerlie is also a scientist at the Samuel Lunenfeld Research Institute, one of the world’s leading academic centres in biomedical research, particularly in functional genomics and transgenic mouse and embryonic stem cell technologies to generate animal models of human disease.