Pr. Butler is developing the Know-It-All framework for database systems. In bioinformatics, they plan to apply this framework to construct knowledge-bases of the metabolic pathways and signal networks of model organisms. Dr Butler's research goal is to construct knowledge-based scientific work environments, especially those for genomics and bioinformatics. In order to succeed at this, Dr Butler has been investigating software technology for complex software systems - including software architectures, object-oriented design, and software reuse - to complement his experience in scientific computation and knowledge-based systems.

Pr. Butler is a member of the Centre for Structural and Functional Genomics that obtained significant support from the Canadian Foundation for Innovation and a donation for equipment from BioChem Pharma. The research is supported by an NSERC Genomics grant, and a large project grant from Genome Canada and Genome Quebec for work on fungal genomics.

Greg Butler is Professor in Computer Science at Concordia University, Montreal, Canada. He joined Concordia in 1992 after nine years on the faculty of the University of Sydney, Australia. Pr Butler has broad international experience, including periods visiting the University of Delaware, Universität Bayreuth, Universität Karlsruhe, and RMIT, Melbourne. Pr Butler has consulted on object-oriented design, object technology, and extensible software architectures.