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Functional genomics, kinomics, diabetes, islet biology
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Researcher Information
Scientist, Assistant Professor
Pediatrics, BMI
Website
401 Smyth Road
Ottawa, Ontario
Canada K1H 8L1
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Robert Screaton received his undergraduate and graduate training at McGill University in Montreal, Canada (1998), and pursued post-doctoral studies at the Burnham Institute (1999-2002) and the Salk Institute (2002-2005) in San Diego, California. Dr. Screaton joined the Apoptosis Research Centre at the Children's Hospital of Eastern Ontario Research Institute and the University of Ottawa in July 2005. He is the recipient of awards such as the Canada Research Chair In Apoptotic Signaling, Tier II (2006-2011) and Ontario Early Researcher Award (2006-2011).
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Researcher Information
Scientist, Assistant Professor
Pediatrics, BMI
Website
401 Smyth Road
Ottawa, Ontario
Canada K1H 8L1
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Jhala, U., Canettieri, G., Screaton, R.A., Kulkarni, R.N., Krajewski, S., Reed, J., Walker, J., Lin, X., White, M., and Montminy, M. cAMP Promotes Pancreatic Beta Cell Survival via CREB Mediated Induction of IRS2. Genes Dev. 17(13): 1575-1580 (2003).
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Conkright, M.D., Canettieri, G., Screaton, R., Guzman, E., Miraglia, L., Hogenesch, J., Montminy, M. TORCs: Novel Transducers of Regulated CREB Activity. Mol. Cell 12: 413-23 (2003).
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Screaton R.A., Conkright, M.D., Katoh, Y., Best, J., Canettieri, G., Jeffries, S., Guzman, E., Niessen, S., Yates, J.R. III, Takemori, H., Okamoto, M., Montminy, M..The CREB Coactivator TORC2 Functions as a Calcium and cAMP Sensitive Coincidence Detector. Cell 119: 61-74 (2004).
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Koo, S-H, Flechner, L., Qi, L., Zhang, X., Screaton, R.A., Jeffries, S., Hedrick, S., Xu, W., Boussouar, F., Brindle, P., Takemori, H., and Montminy, M. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437:1109-11 (2005).
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Jansson, D., Cheuk-Him Ng, A., Fu, A., Depatie, C., Al Azzabi, M, and Screaton, R.A. Glucose Controls CREB Activity in Islet Cells via Regulated Phosphorylation of TORC2. PNAS 105: 10161-10166 (2008).
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Researcher Information
Scientist, Assistant Professor
Pediatrics, BMI
Website
401 Smyth Road
Ottawa, Ontario
Canada K1H 8L1
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YOU MAY ALSO BE INTERESTED IN:
CATEGORIES
Disciplinary Focus
Experimental biology and chemistry
Core Technology
Kinomic screens. In vitro and cell based.
Cells and tissues:
Cell imaging
Nucleic acids:
DNA sequencing,
Gene expression systems,
Microarrays,
RNA technologies
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