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Scott Tanner continues to evolve the instrumentation, reagents and methods of mass cytometry for massively multi-parameter analysis of single cells. The technology is now available worldwide.
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Scott Tanner continues to evolve the instrumentation, reagents and methods of mass cytometry for massively multi-parameter analysis of single cells. The technology is now available worldwide.
EXPLORE >   Researchers >  Scott Tanner
Scott Tanner |
DVS Sciences Inc.
RESEARCH
BIOGRAPHY
KEY PUBLICATIONS
INTELLECTUAL PROPERTY
Research

Continuing evolution of the technology of mass cytometry, that employs atomic mass spectrometry (Inductively Coupled Plasma Mass Spectrometry, ICP-MS) to address the challenges of multi-parameter flow cytometry.  Stable isotopes are used as tags instead of fluorophores.  The resolution of ICP-MS allows many probes to be determined simultaneously, allowing massively multi-parameter and quantitative assay of cell surface and intracellular proteins in single cells at high throughput.

Researcher Information
Chief Technology Officer, co-founder
Website
70 Esna Park Drive, Unit 12
Markham, Ontario
Canada L3R 6E7
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Biography

Scott D. Tanner is co-founder and Chief Technology Officer of DVS Sciences, Inc., a biotech company that develops, manufactures and markets analytical instruments and reagents for high throughput, massively multi-parameter single cell analysis. 

Following receipt of a PhD in physical chemistry from York University (Toronto), he joined Sciex Inc., subsequently MDS Sciex, in 1980 on a Research Fellowship, and stayed for 25 years, eventually becoming Principal Scientist.  He led the development of atomic mass spectrometry instruments that captured nearly 50% of the world market and were sold through the PerkinElmer-Sciex Joint Venture.

Scott, together with his research team, left Sciex in 2005 to assume a faculty appointment at the University of Toronto twhere they took on a new challenge of applying mass spectrometry as a detector for flow cytometry.  DVS Sciences Inc. was established to bring that instrumentation and reagent stream to the market. The company is headquartered in Sunnyvale California and has R&D and production facilities in Toronto.  There are presently multiple CyTOF® Mass Cytometer customers in each of NA, Asia and Europe.

Scott received the University of Toronto 2011 Inventor of the Year Award in Biomedical and Life Sciences, the 2011 ThermoFisher Scientific Spectroscopy Award, the 2003 W.A.E. McBryde Medal, and the 2001 Manning Innovation Foundation Award of Distinction. He is a Fellow of the Royal Society of Chemistry (UK).
Researcher Information
Chief Technology Officer, co-founder
Website
70 Esna Park Drive, Unit 12
Markham, Ontario
Canada L3R 6E7


Key Publications
D. R. Bandura, V. I. Baranov, O. I. Ornatsky, A. Antonov, R. Kinach, X. D. Lou, S. Pavlov, S. Vorobiev, J. E. Dick, S. D. Tanner. Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry. Analytical Chemistry, 2009, 81: 6813-682.
Sean C. Bendall, Erin F. Simonds, Peng Qiu, El-ad D. Amir, Peter O. Krutzik, Rachel Finck, Robert V. Bruggner, Rachel Melamed, Angelica Trejo, Olga I. Ornatsky, Robert S. Balderas, Sylvia K. Plevritis, Karen Sachs, Dana Pe’er, Scott D. Tanner, Garry P. Nolan. Single-cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum. Science, 2011, 332: 687-696
O. Ornatsky, D. Bandura, V. Baranov, M. Nitz., M.A. Winnik and S. Tanner. Highly multiparametric analysis by mass cytometry. Journal of Immunological Methods, 2010, 361: 1-20.
O.I. Ornatsky, X. Lou, M. Nitz, S. Schäfer, W.S. Sheldrick, V.I. Baranov, D.R. Bandura, S.D. Tanner. Study of Cell Antigens and Intracellular DNA by Identification of Element-Containing Labels and Metallointercalators Using Inductively Coupled Plasma Mass Spectrometry. Analytical Chemistry, 2008, 80: 2539-2547.
S.D. Tanner, O. Ornatsky, D.R. Bandura and V.I. Baranov. Multiplex Bio-Assay with Inductively Coupled Plasma Mass Spectrometry: Towards a Massively Multivariate Single Cell Technology, Spectrochimica Acta Part B, 2007, 62: 188-195.
Researcher Information
Chief Technology Officer, co-founder
Website
70 Esna Park Drive, Unit 12
Markham, Ontario
Canada L3R 6E7


Intellectual Property

Researcher Information
Chief Technology Officer, co-founder
Website
70 Esna Park Drive, Unit 12
Markham, Ontario
Canada L3R 6E7
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CATEGORIES
Application Area
Instrumentation and tools
Research Paradigm
Large-scale projects, Technology development
Core Technology
Any other technology: Mass Cytometry: cytometry with atomic mass spectrometer detection
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